Does St. John's wort help with fatigue during perimenopause?

Some women find that St. John's wort helps manage fatigue during perimenopause, though individual results vary. The connection between St. John's wort and fatigue involves how this supplement interacts with the hormonal and neurochemical pathways that become disrupted during perimenopause.

The evidence for using St. John's wort specifically for fatigue ranges from anecdotal reports to clinical studies. What matters most is whether it works for your body. Many supplements need 4 to 8 weeks of consistent use before you can fairly evaluate their effect on symptoms like fatigue.

If you want to try St. John's wort for fatigue: Start with a lower dose, choose a reputable brand with third-party testing, and track your fatigue severity daily so you have objective data. Continue your other management strategies (sleep, exercise, stress reduction) while testing St. John's wort so you can isolate its effect.

Always check with your healthcare provider before starting St. John's wort, especially if you take other medications or have existing health conditions.