Symptom & Goal

Cardio for Anxiety During Perimenopause: How Exercise Calms the Nervous System

Learn how cardio exercise reduces anxiety in perimenopause through endorphins, lower cortisol, and better sleep. Plus tips for getting started.

5 min readFebruary 27, 2026

Why Anxiety Spikes During Perimenopause

Anxiety is one of the most commonly reported symptoms of perimenopause, yet many women are not warned it is coming. It can show up as a general sense of unease, racing thoughts at night, sudden nervousness before situations that never bothered you before, or a low-grade tension that never fully lifts. The hormonal explanation involves estrogen's role in regulating neurotransmitters. Estrogen supports serotonin, GABA, and dopamine, which are chemicals that help the brain stay calm and balanced. As estrogen fluctuates and drops during perimenopause, this chemical regulation becomes less stable. The amygdala, the brain's threat-detection center, becomes more reactive. Cortisol levels also tend to run higher during this life stage, adding to the physiological sense of being on edge. The result is anxiety that can feel disproportionate to actual circumstances.

How Cardio Addresses Anxiety at the Biological Level

Cardiovascular exercise is one of the most evidence-backed non-pharmacological treatments for anxiety. Its effects operate through several pathways at once. First, exercise triggers the release of endorphins and endocannabinoids, the brain's natural mood-regulating chemicals. The endocannabinoid anandamide, sometimes called the bliss molecule, rises significantly after moderate aerobic exercise and produces a calming effect that lasts for hours. Second, regular cardio lowers baseline cortisol over time. The body adapts to the mild stress of exercise and becomes better at regulating its stress response overall. Third, aerobic exercise promotes BDNF, which is brain-derived neurotrophic factor, a protein that supports neuroplasticity and emotional resilience. Fourth, cardio improves sleep quality, and poor sleep is one of the biggest drivers of anxiety in perimenopausal women.

Which Types of Cardio Work Best for Anxiety

For anxiety specifically, the research suggests that moderate-intensity sustained aerobic exercise produces the strongest anti-anxiety effects. This means activities where you raise your heart rate to about 60 to 70 percent of maximum and sustain that for at least 20 to 30 minutes. Walking briskly, swimming, cycling, dancing, and light jogging all fit this description. Very high-intensity exercise, like intense interval training, can temporarily raise anxiety in some women, particularly in perimenopause when the cortisol stress response is already elevated. If you notice that a very intense workout leaves you feeling wired rather than calm, dial back the intensity and stick to moderate effort. Outdoor exercise adds the bonus of nature exposure, which research consistently shows reduces the activity of the brain's anxiety centers.

What the Research Shows

A 2015 meta-analysis published in Depression and Anxiety reviewed 49 studies and found that exercise significantly reduced anxiety across all populations studied. The effects were comparable to cognitive behavioral therapy in some comparisons. A 2020 study published in Menopause found that women who exercised regularly during the menopausal transition reported significantly lower anxiety and better psychological wellbeing than sedentary women. A 2023 review in Neuroscience and Biobehavioral Reviews found that aerobic exercise reduces reactivity in the amygdala, meaning the brain's alarm system responds less intensely to potential threats. This is particularly relevant for perimenopausal anxiety, where the amygdala becomes more reactive as estrogen drops.

Getting Started When Anxiety Makes Everything Feel Hard

Starting a cardio routine when you are anxious can feel paradoxically difficult. The very symptom you are trying to address can make motivation and follow-through harder. A few approaches help. Start with something familiar and enjoyable rather than something challenging. A walk you have done before, a dance class with a friend, or a pool you know well lowers the barrier to entry. Set a very small initial goal. Even 10 minutes of movement three times a week is enough to begin shifting your nervous system in the right direction. Pairing exercise with something pleasant, a favourite podcast, a scenic route, or social company, makes it easier to start and more likely you will come back. Over a few weeks, you will likely find that exercise itself becomes a source of calm rather than something that requires effort to do.

Tracking Activity and Anxiety Together

Anxiety can feel constant, making it hard to tell whether exercise is actually making a difference. Logging both your cardio sessions and your daily anxiety levels over time reveals patterns that are invisible day to day. PeriPlan lets you record workouts and track how you are feeling physically and emotionally, so you can look back over weeks and see the bigger picture. Many women are surprised to notice, after a few weeks of consistent tracking, that their anxiety is noticeably lower on days following exercise. That kind of evidence from your own life is motivating in a way that general advice cannot be. It also gives you useful information to bring to your doctor if you are discussing anxiety management options during perimenopause.

Related reading

Symptom & GoalWalking for Anxiety During Perimenopause: A Practical Guide
Symptom & GoalSwimming for Perimenopause Anxiety: A Practical Guide
Symptom & GoalYoga for Perimenopause Anxiety: What Works and Why
Medical disclaimerThis content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare provider with questions about a medical condition. PeriPlan is not a substitute for professional medical advice. If you are experiencing severe or concerning symptoms, please contact your doctor or emergency services immediately.

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